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    Zfp229 zinc finger protein 229 [ Mus musculus (house mouse) ]

    Gene ID: 381067, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Zfp229provided by MGI
    Official Full Name
    zinc finger protein 229provided by MGI
    Primary source
    MGI:MGI:2679295
    See related
    Ensembl:ENSMUSG00000061544 AllianceGenome:MGI:2679295
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in placenta adult (RPKM 4.7), CNS E14 (RPKM 1.8) and 15 other tissues See more
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    Genomic context

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    See Zfp229 in Genome Data Viewer
    Location:
    17 A3.3; 17 11.4 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (21949936..21967950)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (21730955..21748969)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1933 Neighboring gene predicted gene 10509 Neighboring gene zinc finger protein 760 Neighboring gene STARR-seq mESC enhancer starr_42015 Neighboring gene STARR-seq mESC enhancer starr_42017 Neighboring gene zinc finger protein 760 pseudogene Neighboring gene zinc finger protein 820 Neighboring gene predicted gene, 31758

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
    2. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 229

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164676.1 → NP_001158148.1  zinc finger protein 229

      Status: VALIDATED

      Source sequence(s)
      AK147958, BC043476
      Consensus CDS
      CCDS49995.1
      UniProtKB/TrEMBL
      E9PWT2
      Related
      ENSMUSP00000065379.8, ENSMUST00000065871.14
      Conserved Domains (3) summary
      smart00349
      Location:13 → 73
      KRAB; krueppel associated box
      COG5048
      Location:338 → 704
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:481 → 501
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      21949936..21967950
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249864.1 → XP_030105724.1  zinc finger protein 229 isoform X1

      UniProtKB/TrEMBL
      E9PWT2
      Related
      ENSMUSP00000138107.2, ENSMUST00000182603.2
      Conserved Domains (3) summary
      smart00349
      Location:13 → 73
      KRAB; krueppel associated box
      COG5048
      Location:338 → 704
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:481 → 501
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_030249862.1 → XP_030105722.1  zinc finger protein 229 isoform X1

      UniProtKB/TrEMBL
      E9PWT2
      Conserved Domains (3) summary
      smart00349
      Location:13 → 73
      KRAB; krueppel associated box
      COG5048
      Location:338 → 704
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:481 → 501
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_030249863.2 → XP_030105723.1  zinc finger protein 229 isoform X1

      UniProtKB/TrEMBL
      E9PWT2
      Conserved Domains (3) summary
      smart00349
      Location:13 → 73
      KRAB; krueppel associated box
      COG5048
      Location:338 → 704
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:481 → 501
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_030249861.2 → XP_030105721.1  zinc finger protein 229 isoform X1

      UniProtKB/TrEMBL
      E9PWT2
      Conserved Domains (3) summary
      smart00349
      Location:13 → 73
      KRAB; krueppel associated box
      COG5048
      Location:338 → 704
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:481 → 501
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_030249860.2 → XP_030105720.1  zinc finger protein 229 isoform X1

      UniProtKB/TrEMBL
      E9PWT2
      Conserved Domains (3) summary
      smart00349
      Location:13 → 73
      KRAB; krueppel associated box
      COG5048
      Location:338 → 704
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:481 → 501
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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