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    CDA2 chitin deacetylase CDA2 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851017, updated on 25-Jan-2024

    Summary

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    Gene symbol
    CDA2
    Gene description
    chitin deacetylase CDA2
    Primary source
    SGD:S000004299
    Locus tag
    YLR308W
    See related
    AllianceGenome:SGD:S000004299
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables chitin deacetylase activity. Involved in ascospore wall assembly. Predicted to be located in ascospore-type prospore. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (747937..748875)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene chitin deacetylase CDA1 Neighboring gene Dpa10p Neighboring gene Imh1p Neighboring gene Ras family guanine nucleotide exchange factor CDC25

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the Specific Mode of Action of a Chitin Deacetylase and Separation of the Partially Acetylated Chitosan Oligosaccharides. Zhu XY, et al. Mar Drugs, 2019 Jan 22. PMID 30678277, Free PMC Article
    2. Expression, purification, and characterization of a cobalt-activated chitin deacetylase (Cda2p) from Saccharomyces cerevisiae. Martinou A, et al. Protein Expr Purif, 2002 Feb. PMID 11812231
    3. Yeast ascospore wall assembly requires two chitin deacetylase isozymes. Christodoulidou A, et al. FEBS Lett, 1999 Oct 29. PMID 10544249
    4. Two sporulation-specific chitin deacetylase-encoding genes are required for the ascospore wall rigidity of Saccharomyces cerevisiae. Christodoulidou A, et al. J Biol Chem, 1996 Dec 6. PMID 8940152
    5. cda1+, encoding chitin deacetylase is required for proper spore formation in Schizosaccharomyces pombe. Matsuo Y, et al. FEBS Lett, 2005 May 9. PMID 15862318

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables chitin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chitin deacetylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chitin deacetylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chitin deacetylase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables chitin deacetylase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ascospore wall assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ascospore wall assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in ascospore wall assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chitin catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fungal-type cell wall biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in polysaccharide catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in ascospore-type prospore IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    chitin deacetylase CDA2
    NP_013411.1
    • Chitin deacetylase; together with Cda1p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      747937..748875
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182196.1 → NP_013411.1  TPA: chitin deacetylase CDA2 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013411.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VYV2, Q06703
      UniProtKB/TrEMBL
      B3RHI7, B5VNK8, G2WJD1, N1NZZ9
      Conserved Domains (1) summary
      cl15692
      Location:119 → 291
      CE4_SF; Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06703.1

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