ND-51 NADH dehydrogenase (ubiquinone) 51 kDa subunit [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: ND-51provided by FlyBase
Official Full Name: NADH dehydrogenase (ubiquinone) 51 kDa subunitprovided by FlyBase
Primary source: FLYBASE:FBgn0031771
Locus tag: Dmel_CG9140
See related: AllianceGenome:FB:FBgn0031771
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG9140; Dmel\CG9140; dNDUFV1; dNDUFV1A; ND51; NDUFV1; NUBM
Summary: Predicted to enable 4 iron, 4 sulfur cluster binding activity; NADH dehydrogenase (ubiquinone) activity; and nucleotide binding activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be part of mitochondrial respiratory chain complex I. Is expressed in several structures, including adult heart; embryonic/larval midgut; embryonic/larval muscle system; germ layer; and presumptive embryonic/larval system. Used to study mitochondrial complex I deficiency. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 4. Orthologous to human NDUFV1 (NADH:ubiquinone oxidoreductase core subunit V1). [provided by Alliance of Genome Resources, Apr 2022]
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (6060842..6062757, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (6060842..6062757, complement)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables 4 iron, 4 sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables FMN binding	IEA Inferred from Electronic Annotation more info
enables NAD binding	IEA Inferred from Electronic Annotation more info
enables NADH dehydrogenase (ubiquinone) activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mitochondrial electron transport, NADH to ubiquinone	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial electron transport, NADH to ubiquinone	IC Inferred by Curator more info	PubMed
involved_in mitochondrial electron transport, NADH to ubiquinone	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of mitochondrial respiratory chain complex I	IBA Inferred from Biological aspect of Ancestor more info
part_of mitochondrial respiratory chain complex I	IDA Inferred from Direct Assay more info	PubMed
part_of mitochondrial respiratory chain complex I	ISS Inferred from Sequence or Structural Similarity more info

Names: (ubiquinone) 51 kDa subunit; CG9140-PA; CG9140-PB; FBpp0078847; NADH dehydrogenase; NADH ubiquinone oxidoreductase 51 kDa; NADH-UBIQUINONE OXIDOREDUCTASE 51 KDA SUBUNIT; NADH:ubiquinone oxidoreductase 51 kDa subunit; NADH:ubiquinone oxidoreductase, 51kDa subunit; ND-51-PA; ND-51-PB; ubiquinone

NP_001285657.1

NP_608987.1

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain