Ramac RNA guanine-7 methyltransferase activating subunit [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ramacprovided by RGD
Official Full Name: RNA guanine-7 methyltransferase activating subunitprovided by RGD
Primary source: RGD:1310022
See related: Ensembl:ENSRNOG00000019426 AllianceGenome:RGD:1310022
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Rammet; Fam103a1; RGD1310022
Summary: Predicted to enable RNA binding activity and enzyme activator activity. Predicted to be involved in methylation and recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex. Predicted to be located in nucleoplasm. Predicted to be part of mRNA cap binding activity complex and mRNA cap methyltransferase complex. Orthologous to human RAMAC (RNA guanine-7 methyltransferase activating subunit). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Brain (RPKM 193.4), Testes (RPKM 174.5) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q31

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (145117752..145123640)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (135708529..135714417)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (143583675..143589563)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH128455 (e-PCR)
- UniSTS:211763

RH140483 (e-PCR)
- UniSTS:222555

RH132123 (e-PCR)
- UniSTS:215406

RH140017 (e-PCR)
- UniSTS:222099

RH140633 (e-PCR)
- UniSTS:222702

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	ISO Inferred from Sequence Orthology more info
enables enzyme activator activity	ISO Inferred from Sequence Orthology more info
enables molecular function activator activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in 7-methylguanosine mRNA capping	ISO Inferred from Sequence Orthology more info
involved_in RNA 5'-cap (guanine-N7)-methylation	IEA Inferred from Electronic Annotation more info
involved_in biological_process	ND No biological Data available more info
involved_in methylation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of mRNA cap methyltransferase RNMT:RAMAC complex	ISO Inferred from Sequence Orthology more info
part_of mRNA capping enzyme complex	IBA Inferred from Biological aspect of Ancestor more info
part_of mRNA capping enzyme complex	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: RNA guanine-N7 methyltransferase activating subunit

Names: RNMT activating mRNA cap methyltransferase subunit; family with sequence similarity 103, member A1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.