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    Psapl1 prosaposin-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 76943, updated on 3-Apr-2024

    Summary

    Official Symbol
    Psapl1provided by MGI
    Official Full Name
    prosaposin-like 1provided by MGI
    Primary source
    MGI:MGI:1924193
    See related
    Ensembl:ENSMUSG00000043430 AllianceGenome:MGI:1924193
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2310020A21Rik
    Summary
    Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; prostate gland development; and regulation of lipid metabolic process. Predicted to be located in cytosol. Predicted to be active in extracellular space. Is expressed in lower urinary tract; naris; rectum; and vibrissa. Orthologous to human PSAPL1 (prosaposin like 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
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    Genomic context

    Location:
    5 B3; 5 19.14 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (36361365..36363912)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (36204021..36206568)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene sortilin-related VPS10 domain containing receptor 2 Neighboring gene STARR-seq mESC enhancer starr_12872 Neighboring gene predicted gene, 32119 Neighboring gene predicted gene, 31945 Neighboring gene microRNA 7689 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:36701008-36701161 Neighboring gene STARR-positive B cell enhancer mm9_chr5:36715900-36716201 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:36720744-36720945 Neighboring gene RIKEN cDNA 2210406O10 gene

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in epithelial cell differentiation involved in prostate gland development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in prostate gland growth IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of lipid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within sphingolipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sphingolipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    proactivator polypeptide-like 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175249.4NP_780458.3  proactivator polypeptide-like 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AC133937
      Consensus CDS
      CCDS39072.1
      UniProtKB/Swiss-Prot
      Q8BJV5, Q8C1C1, Q8C1N0
      Related
      ENSMUSP00000100594.2, ENSMUST00000052224.6

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      36361365..36363912
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)