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    Prrc1 proline-rich coiled-coil 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291444, updated on 25-Apr-2024

    Summary

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    Official Symbol
    Prrc1provided by RGD
    Official Full Name
    proline-rich coiled-coil 1provided by RGD
    Primary source
    RGD:1565632
    See related
    Ensembl:ENSRNOG00000016433 AllianceGenome:RGD:1565632
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Prcc1
    Summary
    Predicted to enable identical protein binding activity and protein kinase A regulatory subunit binding activity. Predicted to be involved in activation of protein kinase A activity. Predicted to be located in Golgi apparatus. Predicted to be active in cytoplasm. Orthologous to human PRRC1 (proline rich coiled-coil 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Muscle (RPKM 93.6), Lung (RPKM 92.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    18q12.1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (53010606..53047601)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (50812548..50846273)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (52423845..52460854)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 4, regulatory subunit 1, pseudogene 1 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene uncharacterized LOC100910150 Neighboring gene uncharacterized LOC100910189 Neighboring gene cortexin 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Protein-protein interaction panel using mouse full-length cDNAs. Suzuki H, et al. Genome Res, 2001 Oct. PMID 11591653, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC124825

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein kinase A regulatory subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in activation of protein kinase A activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    protein PRRC1
    Names
    proline-rich and coiled-coil-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033887.2 → NP_001029059.2  protein PRRC1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000018
      UniProtKB/Swiss-Prot
      A0A8I6G4Z0, Q3T1I4
      UniProtKB/TrEMBL
      A6IX75, G3V834
      Related
      ENSRNOP00000079201.1, ENSRNOT00000118107.1
      Conserved Domains (1) summary
      cl00866
      Location:261 → 374
      NTPase_I-T; Protein of unknown function DUF84

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      53010606..53047601
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039096645.2 → XP_038952573.1  protein PRRC1 isoform X2

      UniProtKB/TrEMBL
      G3V834
      Related
      ENSRNOP00000022021.5
      Conserved Domains (2) summary
      PHA03247
      Location:50 → 197
      PHA03247; large tegument protein UL36; Provisional
      cl00866
      Location:261 → 381
      NTPase_I-T; Protein of unknown function DUF84

    2. XM_006254746.4 → XP_006254808.1  protein PRRC1 isoform X1

      See identical proteins and their annotated locations for XP_006254808.1

      UniProtKB/Swiss-Prot
      A0A8I6G4Z0, Q3T1I4
      UniProtKB/TrEMBL
      A6IX75, G3V834
      Conserved Domains (1) summary
      cl00866
      Location:261 → 374
      NTPase_I-T; Protein of unknown function DUF84
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3T1I4.2 GenPept UniProtKB/Swiss-Prot:Q3T1I4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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