Cox7b cytochrome c oxidase subunit 7B [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cox7bprovided by RGD
Official Full Name: cytochrome c oxidase subunit 7Bprovided by RGD
Primary source: RGD:727789
See related: Ensembl:ENSRNOG00000054689 AllianceGenome:RGD:727789
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable cytochrome-c oxidase activity. Predicted to be involved in central nervous system development. Predicted to be located in mitochondrial respirasome. Predicted to be integral component of membrane. Predicted to be part of respiratory chain complex IV. Human ortholog(s) of this gene implicated in linear skin defects with multiple congenital anomalies 2. Orthologous to human COX7B (cytochrome c oxidase subunit 7B). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 9705.5), Muscle (RPKM 5890.5) and 7 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: Xq22

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	X	NC_086039.1 (75149036..75155285)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	X	NC_051356.1 (71083486..71089733)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	X	NC_005120.4 (77065427..77071676)

Chromosome X - NC_086039.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in central nervous system development	ISO Inferred from Sequence Orthology more info
involved_in central nervous system development	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrial electron transport, cytochrome c to oxygen	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrial membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrial respirasome	IEA Inferred from Electronic Annotation more info
part_of mitochondrial respiratory chain complex IV	ISO Inferred from Sequence Orthology more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex IV	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: cytochrome c oxidase subunit 7B, mitochondrial

Names: cytochrome c oxidase polypeptide VIIb; cytochrome c oxidase subunit VIIb

NP_877971.2

EC 7.1.1.9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.