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    KRT88 keratin 88 [ Canis lupus familiaris (dog) ]

    Gene ID: 608165, updated on 22-Jan-2024

    Summary

    Gene symbol
    KRT88
    Gene description
    keratin 88
    See related
    Ensembl:ENSCAFG00845026351
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
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    Genomic context

    Location:
    chromosome: 27
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 27 NC_051831.1 (2786337..2791692, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 27 NC_006609.4 (43461441..43466794)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 27 NC_049248.1 (43859638..43864994)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 27 NC_049287.1 (2803087..2808442, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 27 NC_049768.1 (2789223..2794574, complement)

    Chromosome 27 - NC_051831.1Genomic Context describing neighboring genes Neighboring gene keratin 86 Neighboring gene uncharacterized LOC111092820 Neighboring gene keratin 81 Neighboring gene uncharacterized LOC111092819 Neighboring gene keratin, type II cuticular Hb1-like Neighboring gene keratin 7

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables structural constituent of skin epidermis IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in intermediate filament organization IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in keratinization IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in keratin filament IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    keratin, type II cuticular Hb5; keratin, type II cytoskeletal 7; keratin, type II cytoskeletal 8; keratin, type II microfibrillar, component 5
    Names
    keratin, type II cytoskeletal 8-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051831.1 Reference ROS_Cfam_1.0

      Range
      2786337..2791692 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038438117.1XP_038294045.1  keratin, type II cytoskeletal 7 isoform X3

      UniProtKB/TrEMBL
      A0A8C0T2Z8, A0A8I3Q9E8
      Related
      ENSCAFP00845036514.1, ENSCAFT00845046512.1
      Conserved Domains (1) summary
      pfam00038
      Location:3117
      Filament; Intermediate filament protein
    2. XM_038438115.1XP_038294043.1  keratin, type II microfibrillar, component 5 isoform X1

      Conserved Domains (2) summary
      PTZ00449
      Location:123217
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00038
      Location:3117
      Filament; Intermediate filament protein
    3. XM_038438116.1XP_038294044.1  keratin, type II cytoskeletal 8 isoform X2

      UniProtKB/TrEMBL
      A0A8I3PTR1
      Related
      ENSCAFP00845036462.1, ENSCAFT00845046443.1
      Conserved Domains (1) summary
      pfam00038
      Location:3117
      Filament; Intermediate filament protein

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049287.1 Alternate UMICH_Zoey_3.1

      Range
      2803087..2808442 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038512811.1XP_038368739.1  keratin, type II cytoskeletal 7 isoform X3

      Conserved Domains (1) summary
      pfam00038
      Location:3117
      Filament; Intermediate filament protein
    2. XM_038512809.1XP_038368737.1  keratin, type II microfibrillar, component 5 isoform X1

      Conserved Domains (2) summary
      PTZ00449
      Location:123217
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00038
      Location:3117
      Filament; Intermediate filament protein
    3. XM_038512810.1XP_038368738.1  keratin, type II cytoskeletal 8 isoform X2

      Conserved Domains (1) summary
      pfam00038
      Location:3117
      Filament; Intermediate filament protein

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049768.1 Alternate UNSW_CanFamBas_1.0

      Range
      2789223..2794574 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038640574.1XP_038496502.1  keratin, type II cuticular Hb5 isoform X3

    2. XM_038640572.1XP_038496500.1  keratin, type II microfibrillar, component 5 isoform X1

    3. XM_038640573.1XP_038496501.1  keratin, type II cytoskeletal 8 isoform X2

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049248.1 Alternate UU_Cfam_GSD_1.0

      Range
      43859638..43864994
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038577733.1XP_038433661.1  keratin, type II cytoskeletal 8 isoform X2

      UniProtKB/TrEMBL
      A0A8I3PTR1
      Conserved Domains (1) summary
      pfam00038
      Location:3117
      Filament; Intermediate filament protein
    2. XM_038577732.1XP_038433660.1  keratin, type II microfibrillar, component 5 isoform X1

      Conserved Domains (2) summary
      PTZ00449
      Location:123217
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00038
      Location:3117
      Filament; Intermediate filament protein
    3. XM_038577734.1XP_038433662.1  keratin, type II cytoskeletal 7 isoform X3

      UniProtKB/TrEMBL
      A0A8C0T2Z8, A0A8I3Q9E8
      Conserved Domains (1) summary
      pfam00038
      Location:3117
      Filament; Intermediate filament protein

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006609.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      43461441..43466794
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014108366.3XP_013963841.1  keratin, type II cytoskeletal 8 isoform X2

      UniProtKB/TrEMBL
      A0A8I3PTR1
      Conserved Domains (1) summary
      pfam00038
      Location:3117
      Filament; Intermediate filament protein
    2. XM_022411292.2XP_022267000.1  keratin, type II microfibrillar, component 5 isoform X1

      Conserved Domains (2) summary
      PTZ00449
      Location:123217
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam00038
      Location:3117
      Filament; Intermediate filament protein
    3. XM_022411293.2XP_022267001.1  keratin, type II cytoskeletal 7 isoform X3

      UniProtKB/TrEMBL
      A0A8C0T2Z8, A0A8I3Q9E8
      Conserved Domains (1) summary
      pfam00038
      Location:3117
      Filament; Intermediate filament protein