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    Rnf208 ring finger protein 208 [ Mus musculus (house mouse) ]

    Gene ID: 68846, updated on 5-Mar-2024

    Summary

    Official Symbol
    Rnf208provided by MGI
    Official Full Name
    ring finger protein 208provided by MGI
    Primary source
    MGI:MGI:1916096
    See related
    Ensembl:ENSMUSG00000044628 AllianceGenome:MGI:1916096
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110061N23Rik
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein autoubiquitination. Predicted to be located in cytosol and nucleoplasm. Is expressed in nervous system and neural retina. Orthologous to human RNF208 (ring finger protein 208). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
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    Genomic context

    Location:
    2 A3; 2 17.1 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (25132941..25134273)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (25242929..25244261)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene ring finger protein 224 Neighboring gene cysteine rich tail 1 Neighboring gene NADPH dependent diflavin oxidoreductase 1 Neighboring gene transmembrane protein 203 Neighboring gene STARR-positive B cell enhancer ABC_E805 Neighboring gene taperin

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in protein autoubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_176834.2NP_789804.2  RING finger protein 208

      See identical proteins and their annotated locations for NP_789804.2

      Status: VALIDATED

      Source sequence(s)
      AK004344, BQ031423, CX206020
      Consensus CDS
      CCDS15757.2
      UniProtKB/Swiss-Prot
      A2AI04, B2FDG8, Q8BTC4, Q8K0W3
      Related
      ENSMUSP00000109995.2, ENSMUST00000114355.2
      Conserved Domains (1) summary
      cd16559
      Location:144197
      RING-HC_RNF208; RING finger, HC subclass, found in RING finger protein 208 (RNF208) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      25132941..25134273
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)