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    Pcnx4 pecanex homolog 4 [ Mus musculus (house mouse) ]

    Gene ID: 67708, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Pcnx4provided by MGI
    Official Full Name
    pecanex homolog 4provided by MGI
    Primary source
    MGI:MGI:1914958
    See related
    Ensembl:ENSMUSG00000034501 AllianceGenome:MGI:1914958
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pcnxl4; 4932413O10; 1810048J11Rik
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human PCNX4 (pecanex 4). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 6.0), whole brain E14.5 (RPKM 4.7) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    12 C3; 12 30.2 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (72583098..72628555)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (72536152..72580213)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33487 Neighboring gene leucine rich repeat containing 9 Neighboring gene STARR-seq mESC enhancer starr_32441 Neighboring gene lymphocyte antigen 6 family member E, pseudogene 1 Neighboring gene dehydrogenase/reductase 7 like 1 Neighboring gene STARR-seq mESC enhancer starr_32442 Neighboring gene dehydrogenase/reductase 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    2. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    pecanex-like protein 4
    Names
    pecanex homolog protein 4
    pecanex-like 4
    pecanex-like protein C14orf135 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001404745.1 → NP_001391674.1  pecanex-like protein 4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC160936

    2. NM_001404746.1 → NP_001391675.1  pecanex-like protein 4 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC160936

    3. NM_001404747.1 → NP_001391676.1  pecanex-like protein 4 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC160936

    4. NM_001404748.1 → NP_001391677.1  pecanex-like protein 4 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC160936

    5. NM_001404750.1 → NP_001391679.1  pecanex-like protein 4 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC160936

    6. NM_001404752.1 → NP_001391681.1  pecanex-like protein 4 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC160936

    7. NM_001404753.1 → NP_001391682.1  pecanex-like protein 4 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC160936

    8. NM_001404754.1 → NP_001391683.1  pecanex-like protein 4 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC160936

    9. NM_026327.4 → NP_080603.2  pecanex-like protein 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC160936
      Consensus CDS
      CCDS36473.1
      UniProtKB/Swiss-Prot
      Q3TUC5, Q3UVY5, Q8BPG1, Q8VE84, Q9D8P3
      UniProtKB/TrEMBL
      E9QN69
      Related
      ENSMUSP00000038916.7, ENSMUST00000044352.8
      Conserved Domains (1) summary
      pfam05041
      Location:1059 → 1174
      Pecanex_C; Pecanex protein (C-terminus)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      72583098..72628555
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516177.4 → XP_006516240.1  pecanex-like protein 4 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3UVY5.2 GenPept UniProtKB/Swiss-Prot:Q3UVY5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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