U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Syngr Synaptogyrin [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36533, updated on 4-Apr-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Syngrprovided by FlyBase
    Official Full Name
    Synaptogyrinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033876
    Locus tag
    Dmel_CG10808
    See related
    AllianceGenome:FB:FBgn0033876
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10808; Dmel\CG10808; gyr; Gyr; sng-1; synaptogyrin
    Summary
    Involved in synaptic vesicle transport. Predicted to be active in neuromuscular junction and synaptic vesicle membrane. Is expressed in adult head; embryonic/larval central nervous system; and embryonic/larval neuromuscular junction. Orthologous to several human genes including SYNGR1 (synaptogyrin 1) and SYNGR3 (synaptogyrin 3). [provided by Alliance of Genome Resources, Apr 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    50C6-50C6; 2-68 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (13841761..13846255, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (9729266..9733760, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Cathepsin L2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene mir-9379 stem loop

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Two Pathways for the Activity-Dependent Growth and Differentiation of Synaptic Boutons in Drosophila. Vasin A, et al. eNeuro, 2019 Jul/Aug. PMID 31387877, Free PMC Article
    2. Abnormal synaptic vesicle biogenesis in Drosophila synaptogyrin mutants. Stevens RJ, et al. J Neurosci, 2012 Dec 12. PMID 23238721, Free PMC Article
    3. Differential regulation of evoked and spontaneous neurotransmitter release by C-terminal modifications of complexin. Buhl LK, et al. Mol Cell Neurosci, 2013 Jan. PMID 23159779, Free PMC Article
    4. Discovery of insect and human dengue virus host factors. Sessions OM, et al. Nature, 2009 Apr 23. PMID 19396146, Free PMC Article
    5. Ligand binding-dependent functions of the lipocalin NLaz: an in vivo study in Drosophila. Ruiz M, et al. FASEB J, 2014 Apr. PMID 24361577

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in regulation of synaptic vesicle cycle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of synaptic vesicle cycle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in synaptic vesicle exocytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in synaptic vesicle transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in synaptic vesicle transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in neuromuscular junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in neuromuscular junction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in neuromuscular junction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    is_active_in synaptic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    synaptogyrin
    Names
    CG10808-PA
    Syngr-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      13841761..13846255 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137064.3 → NP_610908.1  synaptogyrin [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610908.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7JYV2
      Related
      FBpp0086771
      Conserved Domains (1) summary
      pfam01284
      Location:34 → 169
      MARVEL; Membrane-associating domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JYV2.1 Q7JYV2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous