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    Rnaseh2c ribonuclease H2, subunit C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100361939, updated on 13-Apr-2024

    Summary

    Official Symbol
    Rnaseh2cprovided by RGD
    Official Full Name
    ribonuclease H2, subunit Cprovided by RGD
    Primary source
    RGD:2319141
    See related
    AllianceGenome:RGD:2319141
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in RNA catabolic process. Predicted to be part of ribonuclease H2 complex. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Orthologous to human RNASEH2C (ribonuclease H2 subunit C). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 107.3), Spleen (RPKM 88.7) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Rnaseh2c in Genome Data Viewer
    Location:
    1q43
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (212323916..212325011)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (202894626..202895675)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (220966626..220967717)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene ovo like transcriptional repressor 1 Neighboring gene adaptor related protein complex 5 subunit beta 1 Neighboring gene lysine acetyltransferase 5 Neighboring gene RELA proto-oncogene, NF-kB subunit

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in RNA catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in RNA catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of ribonuclease H2 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of ribonuclease H2 complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ribonuclease H2 subunit C
    Names
    AYP1 protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001401703.1NP_001388632.1  ribonuclease H2 subunit C

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A6HZ77

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      212323916..212325011
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063282447.1XP_063138517.1  ribonuclease H2 subunit C isoform X1