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    Glmp glycosylated lysosomal membrane protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 295231, updated on 5-Mar-2024

    Summary

    Official Symbol
    Glmpprovided by RGD
    Official Full Name
    glycosylated lysosomal membrane proteinprovided by RGD
    Primary source
    RGD:1303130
    See related
    Ensembl:ENSRNOG00000019281 AllianceGenome:RGD:1303130
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1303130; 0610031j06rik
    Summary
    Predicted to be involved in positive regulation of transcription by RNA polymerase II; protein localization to lysosome; and protein stabilization. Predicted to be located in cytosol and nucleus. Predicted to be integral component of membrane. Predicted to be active in lysosome. Orthologous to human GLMP (glycosylated lysosomal membrane protein). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 301.1), Adrenal (RPKM 157.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    Location:
    2q34
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (176092098..176095688)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (173794273..173797863)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (187697528..187701118)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene chaperonin containing TCP1 subunit 3 Neighboring gene small nucleolar RNA SNORA2/SNORA34 family Neighboring gene ATP synthase subunit g, mitochondrial pseudogene Neighboring gene transmembrane protein 79 Neighboring gene SMG5 nonsense mediated mRNA decay factor

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • MGC94430

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization to lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization to lysosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein stabilization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein stabilization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in lysosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    glycosylated lysosomal membrane protein
    Names
    kidney predominant protein NCU-G1
    lysosomal protein NCU-G1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004226.1NP_001004226.1  glycosylated lysosomal membrane protein precursor

      See identical proteins and their annotated locations for NP_001004226.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079294
      UniProtKB/Swiss-Prot
      Q68FV6
      UniProtKB/TrEMBL
      A0A8I6ADT3, A6J663
      Related
      ENSRNOP00000026152.4, ENSRNOT00000026153.6
      Conserved Domains (1) summary
      pfam15065
      Location:54379
      NCU-G1; Lysosomal transcription factor, NCU-G1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      176092098..176095688
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)