Nanp N-acetylneuraminic acid phosphatase [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Nanpprovided by RGD
Official Full Name: N-acetylneuraminic acid phosphataseprovided by RGD
Primary source: RGD:1306009
See related: Ensembl:ENSRNOG00000008307 AllianceGenome:RGD:1306009
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Hdhd4; RGD1306009
Summary: Enables N-acylneuraminate-9-phosphatase activity. Involved in N-acetylneuraminate biosynthetic process. Orthologous to human NANP (N-acetylneuraminic acid phosphatase). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Spleen (RPKM 49.5), Thymus (RPKM 37.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 3q41

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (160289269..160302001, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (139826549..139841655, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (146800018..146812988, complement)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables N-acylneuraminate-9-phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables N-acylneuraminate-9-phosphatase activity	IDA Inferred from Direct Assay more info	PubMed
enables N-acylneuraminate-9-phosphatase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in N-acetylglucosamine biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in N-acetylneuraminate biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in N-acetylneuraminate biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
involved_in N-acetylneuraminate biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in dephosphorylation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: N-acylneuraminate-9-phosphatase

Names: haloacid dehalogenase-like hydrolase domain containing 4; neu5Ac-9-Pase

NP_001009409.1

EC 3.1.3.29

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.