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    AT5G61670 orange protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836289, updated on 15-Oct-2023

    Summary

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    Gene symbol
    AT5G61670
    Gene description
    orange protein
    Primary source
    Araport:AT5G61670
    Locus tag
    AT5G61670
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K11J9.20; K11J9_20
    Summary
    Encodes a close homolog of the Cauliflower OR (Orange) protein. The function of OR is to induce the differentiation of proplastids or other noncolored plastids into chromoplasts for carotenoid accumulation. Both proteins contain a Cysteine-rich zinc finger domain that is highly specific to DnaJ-like molecular chaperons.
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    Genomic context

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    See AT5G61670 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (24783429..24786265)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene glycine-rich protein Neighboring gene CYCLIN P4;2 Neighboring gene ncRNA Neighboring gene Pectin lyase-like superfamily protein Neighboring gene ABC2 homolog 15 Neighboring gene ABC2 homolog 16

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The DnaJ-like Zinc Finger Protein ORANGE Promotes Proline Biosynthesis in Drought-Stressed Arabidopsis Seedlings. Ali F, et al. Int J Mol Sci, 2022 Mar 31. PMID 35409266, Free PMC Article
    2. Arabidopsis ORANGE protein regulates plastid pre-protein import through interacting with Tic proteins. Yuan H, et al. J Exp Bot, 2021 Feb 24. PMID 33165598
    3. Ectopic expression of ORANGE promotes carotenoid accumulation and fruit development in tomato. Yazdani M, et al. Plant Biotechnol J, 2019 Jan. PMID 29729208, Free PMC Article
    4. The DnaJ-like zinc finger domain protein ORANGE localizes to the nucleus in etiolated cotyledons of Arabidopsis thaliana. Sun TH, et al. Protoplasma, 2016 Nov. PMID 26634929
    5. A Single Amino Acid Substitution in an ORANGE Protein Promotes Carotenoid Overaccumulation in Arabidopsis. Yuan H, et al. Plant Physiol, 2015 Sep. PMID 26224804, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The DnaJ-like Zinc Finger Protein ORANGE Promotes Proline Biosynthesis in Drought-Stressed Arabidopsis Seedlings.
      Title: The DnaJ-like Zinc Finger Protein ORANGE Promotes Proline Biosynthesis in Drought-Stressed Arabidopsis Seedlings.
    2. Arabidopsis ORANGE protein regulates plastid pre-protein import through interacting with Tic proteins.
      Title: Arabidopsis ORANGE protein regulates plastid pre-protein import through interacting with Tic proteins.
    3. OR(His), a Natural Variant of OR, Specifically Interacts with Plastid Division Factor ARC3 to Regulate Chromoplast Number and Carotenoid Accumulation.
      Title: OR(His), a Natural Variant of OR, Specifically Interacts with Plastid Division Factor ARC3 to Regulate Chromoplast Number and Carotenoid Accumulation.
    4. Arabidopsis thaliana OR physically interacts with the transcription factor TCP14 in the nucleus and represses its transactivation activity. Through this interaction, the nucleus-localized OR negatively regulates expression of EARLY LIGHT-INDUCIBLE PROTEINS (ELIPs), reduces chlorophyll biosynthesis, and delays development of thylakoid membranes in the plastids of germinating cotyledons. [OR] [ORANGE]
      Title: ORANGE Represses Chloroplast Biogenesis in Etiolated Arabidopsis Cotyledons via Interaction with TCP14.
    5. ectopic expression promotes carotenoid accumulation and fruit development in tomato
      Title: Ectopic expression of ORANGE promotes carotenoid accumulation and fruit development in tomato.
    6. AtOR is a dual-targeted protein that mainly localizes in the nucleus in etiolated cotyledons.
      Title: The DnaJ-like zinc finger domain protein ORANGE localizes to the nucleus in etiolated cotyledons of Arabidopsis thaliana.
    7. study demonstrates OR(His/Ala) as powerful tools for carotenoid enrichment in plants, and provides insights into the mechanisms underlying OR(His)-regulated carotenoid accumulation. [OR] [Orange]
      Title: A Single Amino Acid Substitution in an ORANGE Protein Promotes Carotenoid Overaccumulation in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_125561.4
    NM_203246.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within carotene biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within chloroplast organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within chromoplast organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within_negative_effect de-etiolation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of carotenoid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein stabilization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within protein stabilization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to light stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in plastid ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    orange protein
    NP_200975.1
    • BEST Arabidopsis thaliana protein match is: chaperone protein dnaJ-related (TAIR:AT5G06130.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_974975.1
    • BEST Arabidopsis thaliana protein match is: chaperone protein dnaJ-related (TAIR:AT5G06130.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      24783429..24786265
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125561.4 → NP_200975.1  orange protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200975.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FKF4
      UniProtKB/TrEMBL
      A0A178UAP2, A0A5S9YG46
      Conserved Domains (1) summary
      cl21539
      Location:207 → 293
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40

    2. NM_203246.3 → NP_974975.1  orange protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974975.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FKF4
      UniProtKB/TrEMBL
      A0A178UAP2, A0A5S9YG46
      Conserved Domains (1) summary
      cl21539
      Location:207 → 293
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FKF4.1

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