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    Rasl10a RAS-like, family 10, member A [ Mus musculus (house mouse) ]

    Gene ID: 75668, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Rasl10aprovided by MGI
    Official Full Name
    RAS-like, family 10, member Aprovided by MGI
    Primary source
    MGI:MGI:1922918
    See related
    Ensembl:ENSMUSG00000034209 AllianceGenome:MGI:1922918
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2210403B10Rik
    Summary
    Predicted to enable G protein activity and GTP binding activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus and plasma membrane. Orthologous to human RASL10A (RAS like family 10 member A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in ovary adult (RPKM 36.8), cortex adult (RPKM 19.9) and 8 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Rasl10a in Genome Data Viewer
    Location:
    11 A1; 11 3.21 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (5008128..5010385)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (5058128..5060385)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35321 Neighboring gene STARR-seq mESC enhancer starr_28417 Neighboring gene neurofilament, heavy polypeptide Neighboring gene adaptor protein complex AP-1, beta 1 subunit Neighboring gene STARR-positive B cell enhancer ABC_E5205 Neighboring gene predicted gene, 24958 Neighboring gene growth arrest-specific 2 like 1 Neighboring gene Ewing sarcoma breakpoint region 1 Neighboring gene STARR-positive B cell enhancer ABC_E8383 Neighboring gene STARR-positive B cell enhancer ABC_E11468 Neighboring gene rhomboid domain containing 3 Neighboring gene EMI domain containing 1 Neighboring gene predicted gene, 46266

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. High-throughput sequence identification of gene coding variants within alcohol-related QTLs. Ehringer MA, et al. Mamm Genome, 2001 Aug. PMID 11471062
    2. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC130093, MGC130094

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ras-like protein family member 10A
    Names
    Ras-like protein RRP22 (RAS-related protein on chromosome 22)
    ras-related protein on chromosome 22 homolog
    NP_001350108.1
    NP_660251.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001363179.1 → NP_001350108.1  ras-like protein family member 10A isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL645522
      Conserved Domains (1) summary
      cl21455
      Location:5 → 113
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. NM_145216.4 → NP_660251.1  ras-like protein family member 10A isoform 1

      See identical proteins and their annotated locations for NP_660251.1

      Status: VALIDATED

      Source sequence(s)
      AK044011, AL645522, AV078172
      Consensus CDS
      CCDS24394.1
      UniProtKB/Swiss-Prot
      Q3KNN0, Q8K5A4
      Related
      ENSMUSP00000048453.2, ENSMUST00000037218.2
      Conserved Domains (2) summary
      smart00173
      Location:6 → 176
      RAS; Ras subfamily of RAS small GTPases
      cl21455
      Location:5 → 203
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      5008128..5010385
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8K5A4.1 GenPept UniProtKB/Swiss-Prot:Q8K5A4

    Gene LinkOut

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