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    USP48 ubiquitin specific peptidase 48 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707110, updated on 5-Mar-2024

    Summary

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    Official Symbol
    USP48provided by VGNC
    Official Full Name
    ubiquitin specific peptidase 48provided by VGNC
    Primary source
    VGNC:VGNC:79149
    See related
    Ensembl:ENSMMUG00000017344
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (202984268..203088190)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (20454570..20561690, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene heparan sulfate proteoglycan 2 Neighboring gene 60S ribosomal protein L31 pseudogene Neighboring gene low density lipoprotein receptor class A domain containing 2 Neighboring gene U7 small nuclear RNA Neighboring gene RAP1 GTPase activating protein Neighboring gene alkaline phosphatase, biomineralization associated

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 48

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      202984268..203088190
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015130315.2 → XP_014985801.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X1

      UniProtKB/TrEMBL
      G7MHF0, H9G0M1
      Related
      ENSMMUP00000064491.1, ENSMMUT00000099191.1
      Conserved Domains (3) summary
      cd02668
      Location:90 → 419
      Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd01795
      Location:939 → 1034
      Ubl_USP48; ubiquitin-like (Ubl) domain found in ubiquitin-specific-processing protease 48 (USP48) and similar proteins
      pfam06337
      Location:484 → 554
      DUSP; DUSP domain

    2. XM_015130337.2 → XP_014985823.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X5

      UniProtKB/TrEMBL
      G7MHF0
      Related
      ENSMMUP00000065396.1, ENSMMUT00000095868.1
      Conserved Domains (2) summary
      cd02668
      Location:90 → 419
      Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd01795
      Location:873 → 968
      Ubl_USP48; ubiquitin-like (Ubl) domain found in ubiquitin-specific-processing protease 48 (USP48) and similar proteins

    3. XM_028838370.1 → XP_028694203.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X4

      UniProtKB/TrEMBL
      G7MHF0
      Conserved Domains (3) summary
      cd02668
      Location:90 → 359
      Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      pfam06337
      Location:424 → 494
      DUSP; DUSP domain
      cd01795
      Location:879 → 974
      Ubl_USP48; ubiquitin-like (Ubl) domain found in ubiquitin-specific-processing protease 48 (USP48) and similar proteins

    4. XM_015130334.2 → XP_014985820.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X3

      UniProtKB/TrEMBL
      G7MHF0
      Conserved Domains (3) summary
      cd02668
      Location:90 → 419
      Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      pfam06337
      Location:484 → 554
      DUSP; DUSP domain
      cl00155
      Location:909 → 983
      UBQ; Ubiquitin-like proteins

    5. XM_015130323.2 → XP_014985809.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X2

      UniProtKB/TrEMBL
      G7MHF0
      Conserved Domains (3) summary
      cd02668
      Location:90 → 418
      Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd01795
      Location:938 → 1033
      Ubl_USP48; ubiquitin-like (Ubl) domain found in ubiquitin-specific-processing protease 48 (USP48) and similar proteins
      pfam06337
      Location:483 → 553
      DUSP; DUSP domain

    6. XM_028838379.1 → XP_028694212.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X6

      UniProtKB/TrEMBL
      G7MHF0
      Conserved Domains (2) summary
      cd02668
      Location:90 → 418
      Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cd01795
      Location:872 → 967
      Ubl_USP48; ubiquitin-like (Ubl) domain found in ubiquitin-specific-processing protease 48 (USP48) and similar proteins

    7. XM_015130345.2 → XP_014985831.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X7

      UniProtKB/TrEMBL
      G7MHF0
      Conserved Domains (5) summary
      cd01795
      Location:740 → 846
      USP48_C; USP ubiquitin-specific protease
      cd02668
      Location:1 → 230
      Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      pfam00443
      Location:1 → 229
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam06337
      Location:295 → 365
      DUSP; DUSP domain
      cl12116
      Location:548 → 591
      DUSP; DUSP domain
    Nucleotide Protein
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