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    NOX5 NADPH oxidase 5 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694875, updated on 5-Mar-2024

    Summary

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    Official Symbol
    NOX5provided by VGNC
    Official Full Name
    NADPH oxidase 5provided by VGNC
    Primary source
    VGNC:VGNC:82198
    See related
    Ensembl:ENSMMUG00000006230
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human all
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    Genomic context

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    Location:
    chromosome: 7
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (45714568..45761967)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (45969863..46013163)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene anamorsin pseudogene Neighboring gene sperm equatorial segment protein 1 Neighboring gene ATP-binding cassette sub-family G member 2 pseudogene Neighboring gene uncharacterized LOC114679438 Neighboring gene uncharacterized LOC100431083

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables superoxide-generating NAD(P)H oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in superoxide anion generation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of NADPH oxidase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NADPH oxidase 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      45714568..45761967
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015142557.2 → XP_014998043.2  NADPH oxidase 5

      UniProtKB/TrEMBL
      F7HJ97, G7MY30
      Related
      ENSMMUP00000008193.4, ENSMMUT00000008718.4
      Conserved Domains (3) summary
      cd06186
      Location:420 → 737
      NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
      COG5126
      Location:41 → 164
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
      pfam01794
      Location:268 → 374
      Ferric_reduct; Ferric reductase like transmembrane component
    Nucleotide Protein
    Heading Accession and Version

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