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GTR Home > Conditions/Phenotypes > Hairy cell leukemia

Summary

A rare, slowly progressive, chronic leukemia characterized by presence of abnormal B-lymphocytes (medium sized with abundant irregular pale cytoplasm, hair-like cytoplasmic projections/ruffled cytoplasmic border, a round or bean-shaped nucleus and absent nucleoli) in the blood or bone marrow, spleen and peripheral blood pancytopenia, notable monocytopenia, and marked susceptibility to infection. The characteristic immunophenotype is CD11c+, CD25+, CD103+ and CD123+ with a BRAF mutation in most cases. [from ORDO]

Available tests

9 tests are in the database for this condition.

Check Related conditions for additional relevant tests.

Practice guidelines

  • NCCN, 2022
    NCCN Clinical Practice Guidelines in Oncology (NCCN GuidelinesĀ®) Hairy Cell Leukemia, 2022

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