U.S. flag

An official website of the United States government

GTR Home > Conditions/Phenotypes > Hereditary cancer-predisposing syndrome


An inherited genetic condition in which members within a family are at an increased risk for the development of benign and/or malignant neoplasms. [from NCI]

Genes See tests for all associated and related genes

  • Also known as: BROVCA5, FANCN, PNCA3, PALB2
    Summary: partner and localizer of BRCA2

IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.