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GTR Home > Conditions/Phenotypes > Neoplasm of ovary

Neoplasm of ovary

Synonyms
OVARIAN CANCER, SOMATIC; Ovarian Neoplasms; Ovarian neoplasm; Ovarian tumor

Summary

Ovarian cancer, the leading cause of death from gynecologic malignancy, is characterized by advanced presentation with loco-regional dissemination in the peritoneal cavity and the rare incidence of visceral metastases (Chi et al., 2001). These typical features relate to the biology of the disease, which is a principal determinant of outcome (Auersperg et al., 2001). Epithelial ovarian cancer is the most common form and encompasses 5 major histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Epithelial ovarian cancer arises as a result of genetic alterations sustained by the ovarian surface epithelium (Stany et al., 2008; Soslow, 2008). [from OMIM]

Available tests

138 tests are in the database for this condition.

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Clinical tests (138 available)

Cytogenetics Tests

Molecular Genetics Tests

Genes See tests for all associated and related genes

  • Also known as: AKT, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA, AKT1
    Summary: AKT serine/threonine kinase 1

  • Also known as: Arc-1, BCDS1, CD324, CDHE, ECAD, LCAM, UVO, CDH1
    Summary: cadherin 1

  • Also known as: CTNNB, EVR7, MRD19, NEDSDV, armadillo, CTNNB1
    Summary: catenin beta 1

  • Also known as: CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2), ERBB2
    Summary: erb-b2 receptor tyrosine kinase 2

  • Also known as: IGLON1, OBCAM, OPCM, OPCML
    Summary: opioid binding protein/cell adhesion molecule like

  • Also known as: CCM4, CLAPO, CLOVE, CWS5, HMH, MCAP, MCM, MCMTC, PI3K, PI3K-alpha, p110-alpha, PIK3CA
    Summary: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

  • Also known as: AR-JP, LPRS2, PARK2, PDJ, PRKN
    Summary: parkin RBR E3 ubiquitin protein ligase

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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