U.S. flag

An official website of the United States government

GTR Home > Conditions/Phenotypes > Oocyte/zygote/embryo maturation arrest 21

Oocyte/zygote/embryo maturation arrest 21

Summary

Oocyte/zygote/embryo maturation arrest-21 (OZEMA21) is characterized by female infertility caused by zygote arrest due to pronuclei fusion failure (Zhang et al., 2021). For a discussion of genetic heterogeneity of OZEMA, see 615774. [from OMIM]

Genes See tests for all associated and related genes

  • Also known as: CHK1, OZEMA21, CHEK1
    Summary: checkpoint kinase 1

IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.