ADAM10 ADAM metallopeptidase domain 10
Gene ID: 102, updated on 11-Apr-2024Gene type: protein coding
Also known as: RAK; kuz; AD10; AD18; MADM; CD156c; CDw156; HsT18717
- See all available tests in GTR for this gene
- Go to complete Gene record for ADAM10
- Go to Variation Viewer for ADAM10 variants
Summary
Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing. [provided by RefSeq, Feb 2016]
Associated conditions
Genomic context
- Location:
- 15q21.3
- Sequence:
- Chromosome: 15; NC_000015.10 (58588809..58749707, complement)
- Total number of exons:
- 16
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for ADAM10 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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