TFG trafficking from ER to golgi regulator

Gene ID: 10342, updated on 7-Apr-2024
Gene type: protein coding
Also known as: TF6; HMSNP; SPG57; TRKT3

Summary

There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]

Associated conditions

See all available tests in GTR for this gene

Description	Tests
Hereditary motor and sensory neuropathy, Okinawa type MedGen: C1858338OMIM: 604484GeneReviews: Not available	See labs
Hereditary spastic paraplegia 57 MedGen: C3714897OMIM: 615658GeneReviews: Not available	See labs

Genomic context

Location:: 3q12.2

Sequence:: Chromosome: 3; NC_000003.12 (100709290..100748967)

Total number of exons:: 10

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Variation

Resource	Links for this gene
ClinVar	Variants reported to ClinVar
dbVar	Studies and variants
SNP	Variation Viewer for TFG variants
Genome viewer	Explore NCBI-annotated and select non-NCBI annotated genome assemblies

Links

ClinVar
Related medical variations
dbVar
Link from Gene to dbVar
MedGen
Related information in MedGen
OMIM
Link to related OMIM entry
PubMed (OMIM)
Gene links to PubMed derived from omim_pubmed_cited links
RefSeq RNAs
Link to Nucleotide RefSeq RNAs
RefSeqGene
Link to Nucleotide RefSeqGenes
TFG database
Variation Viewer
Related Variants

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