IL17F interleukin 17F
Gene ID: 112744, updated on 3-Apr-2024Gene type: protein coding
Also known as: ML1; ML-1; IL17A; CANDF6; IL-17F
- See all available tests in GTR for this gene
- Go to complete Gene record for IL17F
- Go to Variation Viewer for IL17F variants
Summary
The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. GeneReviews: Not available | |
| Candidiasis, familial, 6 | See labs |
Genomic context
- Location:
- 6p12.2
- Sequence:
- Chromosome: 6; NC_000006.12 (52236681..52245689, complement)
- Total number of exons:
- 4
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for IL17F variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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