VSIG4 V-set and immunoglobulin domain containing 4
Gene ID: 11326, updated on 5-Mar-2024Gene type: protein coding
Also known as: CRIg; Z39IG
- See all available tests in GTR for this gene
- Go to complete Gene record for VSIG4
- Go to Variation Viewer for VSIG4 variants
Summary
This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Genomic context
- Location:
- Xq12
- Sequence:
- Chromosome: X; NC_000023.11 (66021738..66040080, complement)
- Total number of exons:
- 8
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for VSIG4 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
- VSIG4 @ LOVD
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