ADRB3 adrenoceptor beta 3
Gene ID: 155, updated on 2-May-2024Gene type: protein coding
Also known as: BETA3AR
- See all available tests in GTR for this gene
- Go to complete Gene record for ADRB3
- Go to Variation Viewer for ADRB3 variants
Summary
The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Obesity and bodyweight-related disorders are correlated with certain polymorphisms in three subtypes of beta-adrenoceptor, among them, the ADRB3 gene.[provided by RefSeq, Oct 2019]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Inherited obesity | See labs |
Genomic context
- Location:
- 8p11.23
- Sequence:
- Chromosome: 8; NC_000008.11 (37962990..37966599, complement)
- Total number of exons:
- 2
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for ADRB3 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ADRB3 database
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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