RASGEF1A RasGEF domain family member 1A
Gene ID: 221002, updated on 11-Apr-2024Gene type: protein coding
Also known as: CG4853
- See all available tests in GTR for this gene
- Go to complete Gene record for RASGEF1A
- Go to Variation Viewer for RASGEF1A variants
Summary
Enables guanyl-nucleotide exchange factor activity. Involved in cell migration and positive regulation of Ras protein signal transduction. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| A genome-wide association study identifies potential susceptibility Loci for hirschsprung disease. GeneReviews: Not available | |
| Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. GeneReviews: Not available | |
| Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease. GeneReviews: Not available | |
| Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. GeneReviews: Not available |
Genomic context
- Location:
- 10q11.21
- Sequence:
- Chromosome: 10; NC_000010.11 (43194535..43267065, complement)
- Total number of exons:
- 16
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for RASGEF1A variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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