FER FER tyrosine kinase
Gene ID: 2241, updated on 11-Apr-2024Gene type: protein coding
Also known as: TYK3; PPP1R74; p94-Fer
- See all available tests in GTR for this gene
- Go to complete Gene record for FER
- Go to Variation Viewer for FER variants
Summary
The protein encoded by this gene is a member of the FPS/FES family of non-transmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Apr 2015]
Associated conditions
See all available tests in GTR for this gene
Description | Tests |
---|---|
Hundreds of variants clustered in genomic loci and biological pathways affect human height. GeneReviews: Not available | |
Novel locus FER is associated with serum HMW adiponectin levels. GeneReviews: Not available |
Genomic context
- Location:
- 5q21.3
- Sequence:
- Chromosome: 5; NC_000005.10 (108747897..109196841)
- Total number of exons:
- 33
Variation
Resource | Links for this gene |
---|---|
ClinVar | Variants reported to ClinVar |
dbVar | Studies and variants |
SNP | Variation Viewer for FER variants |
Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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