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NNT nicotinamide nucleotide transhydrogenase

Gene ID: 23530, updated on 25-Nov-2021
Gene type: protein coding
Also known as: GCCD4

Summary

This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. [provided by RefSeq, Sep 2016]

Genomic context

Location:
5p12
Sequence:
Chromosome: 5; NC_000005.10 (43601092..43707396)
Total number of exons:
26

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