TIPARP TCDD inducible poly(ADP-ribose) polymerase
Gene ID: 25976, updated on 11-Apr-2024Gene type: protein coding
Also known as: PARP7; ARTD14; pART14
- See all available tests in GTR for this gene
- Go to complete Gene record for TIPARP
- Go to Variation Viewer for TIPARP variants
Summary
This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. GeneReviews: Not available | |
| Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. GeneReviews: Not available | |
| GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. GeneReviews: Not available |
Genomic context
- Location:
- 3q25.31
- Sequence:
- Chromosome: 3; NC_000003.12 (156674590..156706770)
- Total number of exons:
- 11
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for TIPARP variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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