HELLS helicase, lymphoid specific

Gene ID: 3070, updated on 11-Apr-2024
Gene type: protein coding
Also known as: LSH; ICF4; PASG; SALNR; SMARCA6; Nbla10143

Summary

This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2014]

Associated conditions

See all available tests in GTR for this gene

Description	Tests
Immunodeficiency-centromeric instability-facial anomalies syndrome 4 MedGen: C4310798OMIM: 616911GeneReviews: Not available	See labs

Genomic context

Location:: 10q23.33

Sequence:: Chromosome: 10; NC_000010.11 (94545788..94613905)

Total number of exons:: 25

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Variation

Resource	Links for this gene
ClinVar	Variants reported to ClinVar
dbVar	Studies and variants
SNP	Variation Viewer for HELLS variants
Genome viewer	Explore NCBI-annotated and select non-NCBI annotated genome assemblies

Links

ClinVar
Related medical variations
dbVar
Link from Gene to dbVar
MedGen
Related information in MedGen
OMIM
Link to related OMIM entry
PubMed (OMIM)
Gene links to PubMed derived from omim_pubmed_cited links
RefSeq RNAs
Link to Nucleotide RefSeq RNAs
RefSeqGene
Link to Nucleotide RefSeqGenes
Variation Viewer
Related Variants

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