IL1RAP interleukin 1 receptor accessory protein
Gene ID: 3556, updated on 11-Apr-2024Gene type: protein coding
Also known as: IL1R3; C3orf13; IL-1RAcP
- See all available tests in GTR for this gene
- Go to complete Gene record for IL1RAP
- Go to Variation Viewer for IL1RAP variants
Summary
This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. GeneReviews: Not available | |
| Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women. GeneReviews: Not available |
Genomic context
- Location:
- 3q28
- Sequence:
- Chromosome: 3; NC_000003.12 (190514085..190659750)
- Total number of exons:
- 17
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for IL1RAP variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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