SLC11A2 solute carrier family 11 member 2

Gene ID: 4891, updated on 3-Apr-2024
Gene type: protein coding
Also known as: DCT1; DMT1; AHMIO1; NRAMP2

Summary

This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010]

Associated conditions

See all available tests in GTR for this gene

Description	Tests
Microcytic anemia with liver iron overload MedGen: C3806153OMIM: 206100GeneReviews: Not available	See labs

Genomic context

Location:: 12q13.12

Sequence:: Chromosome: 12; NC_000012.12 (50952263..51028886, complement)

Total number of exons:: 25

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Variation

Resource	Links for this gene
ClinVar	Variants reported to ClinVar
dbVar	Studies and variants
SNP	Variation Viewer for SLC11A2 variants
Genome viewer	Explore NCBI-annotated and select non-NCBI annotated genome assemblies

Links

ClinVar
Related medical variations
dbVar
Link from Gene to dbVar
MedGen
Related information in MedGen
OMIM
Link to related OMIM entry
PubMed (OMIM)
Gene links to PubMed derived from omim_pubmed_cited links
RefSeq RNAs
Link to Nucleotide RefSeq RNAs
RefSeqGene
Link to Nucleotide RefSeqGenes
SLC11A2 database
Variation Viewer
Related Variants

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