NIN ninein
Gene ID: 51199, updated on 3-Apr-2024Gene type: protein coding
Also known as: SCKL7
- See all available tests in GTR for this gene
- Go to complete Gene record for NIN
- Go to Variation Viewer for NIN variants
Summary
This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Common genetic variation and performance on standardized cognitive tests. GeneReviews: Not available | |
| Genome-wide association study of periodontal health measured by probing depth in adults ages 18-49 years. GeneReviews: Not available | |
| Lupus nephritis susceptibility Loci in women with systemic lupus erythematosus. GeneReviews: Not available | |
| Seckel syndrome 7 | See labs |
Genomic context
- Location:
- 14q22.1
- Sequence:
- Chromosome: 14; NC_000014.9 (50719763..50831503, complement)
- Total number of exons:
- 35
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for NIN variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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