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GLRX5 glutaredoxin 5

Gene ID: 51218, updated on 5-Jan-2022
Gene type: protein coding
Also known as: GRX5; PRSA; SIDBA3; SPAHGC; FLB4739; PR01238; PRO1238; C14orf87


This gene encodes a mitochondrial protein, which is evolutionarily conserved. It is involved in the biogenesis of iron-sulfur clusters, which are required for normal iron homeostasis. Mutations in this gene are associated with autosomal recessive pyridoxine-refractory sideroblastic anemia. [provided by RefSeq, May 2010]

Associated conditions

See all available tests in GTR for this gene

Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.
GeneReviews: Not available
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
GeneReviews: Not available
Sideroblastic anemia 3, pyridoxine-refractory
MedGen: C4225155OMIM: 616860GeneReviews: Not available
See labs
Spasticity, childhood-onset, with hyperglycinemia
MedGen: C4225178OMIM: 616859GeneReviews: Not available
See labs

Genomic context

Chromosome: 14; NC_000014.9 (95535050..95544714)
Total number of exons:


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