NKX2-4 NK2 homeobox 4
Gene ID: 644524, updated on 5-Mar-2024Gene type: protein coding
Also known as: NKX2D; NKX2.4
- See all available tests in GTR for this gene
- Go to complete Gene record for NKX2-4
- Go to Variation Viewer for NKX2-4 variants
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Lupus nephritis susceptibility Loci in women with systemic lupus erythematosus. GeneReviews: Not available |
Genomic context
- Location:
- 20p11.22
- Sequence:
- Chromosome: 20; NC_000020.11 (21395365..21397526, complement)
- Total number of exons:
- 2
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for NKX2-4 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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