CDK11A cyclin dependent kinase 11A
Gene ID: 728642, updated on 7-Apr-2024Gene type: protein coding
Also known as: CDC2L2; CDC2L3; p58GTA; PITSLRE; CDK11-p46; CDK11-p58; CDK11-p110
- See all available tests in GTR for this gene
- Go to complete Gene record for CDK11A
- Go to Variation Viewer for CDK11A variants
Summary
This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Genomic context
- Location:
- 1p36.33
- Sequence:
- Chromosome: 1; NC_000001.11 (1702379..1724357, complement)
- Total number of exons:
- 20
Variation
Resource | Links for this gene |
---|---|
ClinVar | Variants reported to ClinVar |
dbVar | Studies and variants |
SNP | Variation Viewer for CDK11A variants |
Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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