YES1 YES proto-oncogene 1, Src family tyrosine kinase
Gene ID: 7525, updated on 11-Apr-2024Gene type: protein coding
Also known as: Yes; c-yes; HsT441; P61-YES
- See all available tests in GTR for this gene
- Go to complete Gene record for YES1
- Go to Variation Viewer for YES1 variants
Summary
This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. GeneReviews: Not available | |
| Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients. GeneReviews: Not available |
Genomic context
- Location:
- 18p11.32
- Sequence:
- Chromosome: 18; NC_000018.10 (721588..812753, complement)
- Total number of exons:
- 16
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for YES1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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