ZP2 zona pellucida glycoprotein 2
Gene ID: 7783, updated on 23-Mar-2024Gene type: protein coding
Also known as: ZPA; Zp-2; OOMD6; OZEMA6
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- Go to complete Gene record for ZP2
- Go to Variation Viewer for ZP2 variants
Summary
The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed of three glycoproteins with various functions during fertilization and preimplantation development. The glycosylated mature peptide is one of the structural components of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. Female mice lacking this gene do not form a stable zona matrix and are sterile. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Associated conditions
See all available tests in GTR for this gene
Description | Tests |
---|---|
Oocyte maturation defect 6 | See labs |
Genomic context
- Location:
- 16p12.3-p12.2
- Sequence:
- Chromosome: 16; NC_000016.10 (21197450..21214510, complement)
- Total number of exons:
- 20
Variation
Resource | Links for this gene |
---|---|
ClinVar | Variants reported to ClinVar |
dbVar | Studies and variants |
SNP | GeneView ReportGo to Variation Viewer for ZP2 variants |
1000 Genomes | See 1000 Genomes Browser (GRCh37.p13) |
- BioSystemsBioSystems
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- SNP: GeneViewSNPs linked from GeneView
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