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FCRL4 Fc receptor like 4

Gene ID: 83417, updated on 11-Apr-2024
Gene type: protein coding
Also known as: FCRH4; IGFP2; IRTA1; CD307d

Summary

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009]

Genomic context

Location:
1q23.1
Sequence:
Chromosome: 1; NC_000001.11 (157573747..157598085, complement)
Total number of exons:
12

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