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RTN4IP1 reticulon 4 interacting protein 1

Gene ID: 84816, updated on 17-Jan-2022
Gene type: protein coding
Also known as: NIMP; OPA10

Summary

This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, cognitive disability, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Genomic context

Location:
6q21
Sequence:
Chromosome: 6; NC_000006.12 (106559237..106630921, complement)
Total number of exons:
13

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