LINGO1 leucine rich repeat and Ig domain containing 1
Gene ID: 84894, updated on 7-Apr-2024Gene type: protein coding
Also known as: LERN1; MRT64; LRRN6A; UNQ201
- See all available tests in GTR for this gene
- Go to complete Gene record for LINGO1
- Go to Variation Viewer for LINGO1 variants
Summary
Predicted to enable epidermal growth factor receptor binding activity. Predicted to act upstream of or within generation of neurons and protein kinase B signaling. Predicted to be located in plasma membrane. Predicted to be active in extracellular matrix and extracellular space. Implicated in autosomal recessive non-syndromic intellectual disability and glaucoma. [provided by Alliance of Genome Resources, Apr 2022]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| A genome-wide association study of the Protein C anticoagulant pathway. GeneReviews: Not available | |
| Intellectual disability, autosomal recessive 64 | See labs |
| Variant in the sequence of the LINGO1 gene confers risk of essential tremor. GeneReviews: Not available |
Genomic context
- Location:
- 15q24.3
- Sequence:
- Chromosome: 15; NC_000015.10 (77613027..77820900, complement)
- Total number of exons:
- 17
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for LINGO1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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