SCARB1 scavenger receptor class B member 1
Gene ID: 949, updated on 5-Mar-2024Gene type: protein coding
Also known as: CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLCQ6; HDLQTL6
- See all available tests in GTR for this gene
- Go to complete Gene record for SCARB1
- Go to Variation Viewer for SCARB1 variants
Summary
The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2 and facilitates cell entry by the virus, SARS-CoV2. [provided by RefSeq, Oct 2021]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Biological, clinical and population relevance of 95 loci for blood lipids. GeneReviews: Not available | |
| Discovery and refinement of loci associated with lipid levels. GeneReviews: Not available | |
| Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy. GeneReviews: Not available | |
| Genome-wide association study identifies common variants associated with circulating vitamin E levels. GeneReviews: Not available | |
| Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study. GeneReviews: Not available | |
| Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3. GeneReviews: Not available | |
| High density lipoprotein cholesterol level quantitative trait locus 6 | See labs |
Genomic context
- Location:
- 12q24.31
- Sequence:
- Chromosome: 12; NC_000012.12 (124776856..124863864, complement)
- Total number of exons:
- 15
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for SCARB1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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