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GTR Home > Tests > ABCB11 mutation analysis



Molecular Genetics
CSequence analysis of the entire coding region
Bi-directional Sanger Sequence Analysis
  • Applied Biosystems 3730 capillary sequencing instrument

Test development


Test developed by laboratory (no manufacturer test name)

Test procedure


DNA is extracted from the patient specimen, PCR amplification and sequence analysis of the entire coding region/ or indicated exons plus additional flanking intronic or other non-coding sequence. Sanger sequencing is carried out and the sequence is visualized on a capillary sequencer. Sequencing is performed separately in both the forward and reverse directions.


Not provided

Confirmation of results


Confirmation of identified mutations is done in an independent experiment.

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