EGFR Mutation Analysis
Clinical Genetic Test
Help
offered by
GTR Test Accession: Help GTR000522730.2
CAP
PHARMACOGENOMIC
Last updated in GTR: 2016-06-01
Last annual review date for the lab: 2024-04-29 LinkOut
At a Glance
Drug Response
EGFR-related lung cancer; Erlotinib response; Gefitinib response
Genes (1): Help
EGFR (7p11.2)
Molecular Genetics - Targeted variant analysis: PCR with allele specific hybridization
Not provided
Not provided
Not provided
Ordering Information
Offered by: Help
Molecular Genetics Diagnostic Laboratory
View lab's website
Test short name: Help
EGFR
Specimen Source: Help
Who can order: Help
  • Health Care Provider
Contact Policy: Help
Laboratory can only accept contact from health care providers. Patients/families are encouraged to discuss genetic testing options with their health care provider.
How to Order: Help
Test development: Help
Test developed by laboratory (no manufacturer test name)
Informed consent required: Help
Decline to answer
Pre-test genetic counseling required: Help
Decline to answer
Post-test genetic counseling required: Help
Decline to answer
Recommended fields not provided:
Conditions Help
Total conditions: 3
Condition/Phenotype Identifier
Test Targets
Genes Help
Total genes: 1
Gene Associated Condition Germline or Somatic Allele (Lab-provided) Variant in NCBI
Methodology
Total methods: 1
Method Category Help
Test method Help
Instrument
Targeted variant analysis
PCR with allele specific hybridization
Thermo Fisher QuantStudio 7
Clinical Information
Test purpose: Help
Drug Response
Recommended fields not provided:
Technical Information
Test Comments: Help
Mutation panel includes exon 18 (G719A, G719S, G719C), exon 19 deletions, exon 20 (T790M, S768I, insertions), exon 21 (L858R, L861Q)
Availability: Help
Tests performed
Entire test performed in-house
Analytical Validity: Help
analytical sensitivity 3%
Proficiency testing (PT):
Is proficiency testing performed for this test? Help
Yes

Method used for proficiency testing: Help
Formal PT program

PT Provider: Help
American College of Medical Genetics / College of American Pathologists, ACMG/CAP
Recommended fields not provided:
Regulatory Approval
FDA Review: Help
Not provided
Additional Information
Practice guidelines:
Consumer resources:

IMPORTANT NOTE: NIH does not independently verify information submitted to GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.