GTR Home > Tests > Otogenetics Hereditary Cancers

Overview

Test order codeHelp: Oto-InhCa-gtr

Test name

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Otogenetics Hereditary Cancers (Inherited Cancer Panel)

Purpose of the test

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This is a clinical test intended for Help: Diagnosis, Predictive, Risk Assessment, Screening

Condition

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36 conditions tested. Click Indication tab for more information.

How to order

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download test requisition form and submit sample according to instructions.
Order URL Help: https://www.otogenetics.com/forms/Inherited-Cancer-Test-Requisition-GTR.pdf

Specimen source

Buccal swab
Fresh tissue
Frozen tissue
Isolated DNA
Peripheral (whole) blood
Saliva

Methodology

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Molecular Genetics
ESequence analysis of select exons
Next-Generation (NGS)/Massively parallel sequencing (MPS)
  • Illumina Novaseq
  • Custom designed gene panel

Summary of what is tested

39 genes and variants. Click Methodology tab for more information.

Genes

Clinical utility

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Predictive risk information for patient and/or family members

Citations

Clinical validity

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Not provided

Testing strategy

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Next Generation Sequencing 000 download test requisition form and submit sample according to instructions.

Test services

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  • Clinical Testing/Confirmation of Mutations Identified Previously, Order code: Oto-InhCa-gtr

Practice guidelines

  • ACMG/NSGC, 2015
    A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for cancer predisposition assessment.
  • IARC, 2008
    Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test results

Consumer resources

IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.

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