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GTR Home > Tests > Prothrombin 20210G>A

Prothrombin 20210G>A

  • GTR Test IDHelp: GTR000558865.1
  • Last updated: 2021-12-28
  • Annual Review past due read more
  • Test version history

Clinical testHelp for Ischemic stroke
Offered by Molecular Genetics Laboratory

Indication

This is a clinical test intended for Help: Diagnosis

Clinical summary

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Imported from OMIM

A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. It is said to be the third leading cause of death in the United States. Gunel and Lifton (1996) noted that about 20% of strokes are hemorrhagic, resulting in bleeding into the brain. Ischemic strokes, resulting from vascular occlusion, account for the majority of strokes. Bersano et al. (2008) reviewed genetic polymorphisms that have been implicated in the development of stroke. Candidate genes include those involved in hemostasis (see, e.g., F5; 612309), the renin-angiotensin-aldosterone system (see, e.g., ACE; 106180), homocysteine (see, e.g., MTHFR; 607093), and lipoprotein metabolism (see, e.g., APOE; 107741). See also hemorrhagic stroke, or intracerebral hemorrhage (ICH; 614519).

Clinical features

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Imported from Human Phenotype Ontology (HPO)

  • Stroke

Conditions tested

Target population

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Not provided

Clinical validity

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Clinical utility

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Not provided

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