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GTR Home > Tests > MUTYH Sequencing and Deletion/Duplication

Overview

Test order codeHelp: 93944

Test name

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MUTYH Sequencing and Deletion/Duplication

Purpose of the test

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This is a clinical test intended for Help: Diagnosis, Predictive, Risk Assessment, Screening

Condition

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How to order

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Order URL Help: http://www.questdiagnostics.com/

Specimen source

Amniocytes
Amniotic fluid
Buccal swab
Chorionic villi
Cord blood
Fibroblasts
Fresh tissue
Peripheral (whole) blood

Methodology

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Molecular Genetics
DDeletion/duplication analysis
Next-Generation (NGS)/Massively parallel sequencing (MPS)
CSequence analysis of the entire coding region
Next-Generation (NGS)/Massively parallel sequencing (MPS)

Summary of what is tested

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Clinical utility

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Not provided

Clinical validity

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Not provided

Suggested reading

Practice guidelines

  • NICE, 2022
    UK NICE Clinical Guideline CG118, Colorectal cancer prevention: colonoscopic surveillance in adults with ulcerative colitis, Crohn's disease or adenomas, 2022
  • NICE, 2021
    UK NICE Guideline NG151, Colorectal cancer, 2021
  • ACMG ACT, 2019
    American College of Medical Genetics and Genomics, Genomic Testing (Secondary Findings) ACT Sheet, APC Pathogenic Variants (Familial Adenomatous Polyposis [FAP]), 2019
  • EuroGenetest, 2010
    Clinical utility gene card for: MUTYH-associated polyposis (MAP), autosomal recessive colorectal adenomatous polyposis

IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.