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GTR Home > Tests > CYP2D6

Overview

Test name

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CYP2D6 (CYP2D6)

Purpose of the test

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This is a clinical test intended for Help: Drug Response

Condition

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Click Indication tab for more information.

How to order

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Order URL Help: https://www.millenniumhealth.com/services/pgt-testing/test-offerings/

Specimen source

Oral Swab
Saliva

Methodology

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Molecular Genetics
TTargeted variant analysis
RT-PCR

Summary of what is tested

Click Methodology tab for more information.

Clinical utility

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Not provided

Clinical validity

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Not provided

Practice guidelines

  • CPIC, 2021
    Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6, OPRM1, and COMT Genotypes and Select Opioid Therapy
  • DPWG, 2020
    Royal Dutch Pharmacists Association (KNMP). Dutch Pharmacogenetics Working Group (DPWG). Pharmacogenetic Guidelines [Internet]. Netherlands. Codeine - CYP2D6
  • ACOG, 2018
    ACOG Committee Opinion No. 742: Postpartum Pain Management
  • CPIC, 2014
    Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450 2D6 Genotype and Codeine Therapy: 2014 Update. (See 2021 Update)
  • CPNDS, 2013
    Clinical practice guideline: CYP2D6 genotyping for safe and efficacious codeine therapy.
  • CPIC, 2012
    Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Codeine Therapy in the Context of Cytochrome P450 2D6 (CYP2D6) Genotype (See 2021 Update)
  • DPWG, 2011
    Pharmacogenetics: from bench to byte--an update of guidelines.

Consumer resources

IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.